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NITROMETHYLIDENE-CONTAINING PIPERAZINONES AND MORPHOLINONE: SYNTHESIS AND STRUCTURE

Василий В. Пелипко, Руслан И. Байчурин, Константин А. Лысенко, Сергей В. Макаренко
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Abstract


The interactions of alkyl 3-bromo-3-nitroacrylates with 1,2-diaminoethane, 1,2-diaminopropane, 1,2-diaminocyclohexane, and 2aminoethanol were shown to provide a convenient route for the synthesis of six-membered heterocycles – (3Z)-3-(nitromethylidene)piperazin-2-ones and (3Z)-3-(nitromethylidene)morpholin-2-one. The structures of the synthesized heterocycles were characterized by a range of spectral methods and by X-ray structural analysis.

 


Keywords


2-aminoethanol; 1,2-diaminocyclohexane; 1,2-diaminoethane; 1,2-diaminopropane; morpholin-2-one; nitroacrylate; piperazin-2-one.

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