RECENT PROGRESS IN THE DIRECT PHOSPHORYLATION OF PARENT HETEROCYCLES TO CONSTRUCT PHOSPHORYLATED HETEROCYCLES

Abstract

This minireview summarizes the latest progress in the synthesis of phosphorylated heterocycles via the direct phosphorylation of parent heterocycles, covering four parts: 1) dehydrative cross couplings between P(O)–H compounds and alcohols; 2) cross-dehydrogenative couplings with P(O)–H compounds; 3) phospha-Michael or phospha-Mannich reaction, and 4) electrophilic phosphorylation of heterocycles.