1H-PYRIDO[3,2-b]INDOLES. SYNTHESIS AND INVESTIGATION OF SOME THEIR SPECTROSCOPIC AND CHEMICAL PROPERTIES
Abstract
At boiling in trifluoroacetic acid derivatives of 3-cyanovinyl-3-p-nitrophenylaminoindole are cyclized into the corresponding pyrido[3,2-b]indoles as a results of activation of the CN group. Thermal cyclization of ethyl indolylacrylate occurs with participation of the more reactive ethoxycarbonyl group to give 3-cyanopyrido[3,2-b]indole.
Authors: S. Yu. Ryabova, L. M. Alekseeva, and B. G. Granik.
English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (3), pp 301-306
Keywords
indole; indolineacrylic acid; carboline; malononitrile; pyridoindole; cyanoacetonitrile
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv