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THE SYNTHESIS OF 3-NITRO-4H-BENZO[h]CHROMENES

Дмитрий В. Осипов, Алина А. Артеменко, Павел Е. Красников, Виталий А. Осянин
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Abstract


A method for the synthesis of 3-nitro-4H-benzo[h]chromenes was developed based on the reaction of 1-naphthoquinone 2-methides generated in situ from Mannich bases with 4-(2-nitrovinyl)morpholine. It was shown that such nucleophiles as morpholine and 4-bromoaniline add to the double bond of the pyran ring.

 


Keywords


1-naphthoquinone 2-methides; 3-nitro-4H-benzo[h]chromenes; 4-(2-nitrovinyl)morpholine; Mannich bases; push-pull olefins; Diels–Alder reaction; Michael reaction.

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