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1,2,4-TRIAZOLES: SYNTHETIC APPROACHES AND PHARMACOLOGICAL IMPORTANCE

I. A. Al-Masoudi, Y. A. Al-Soud, N. J. Al-Salihi, N. A. Al-Masoudi

Abstract


The synthetic routes of 1,2,4-triazole compounds as well as their pharmacological properties have been described.  The review focuses intensively on two methods: cycloaddition reaction in the syntheses of various 1,5-dialky-1H-1,2,4-triazole derivatives from the reactive cumulenes with the nitrile precursors as well as the microwave irradiation method.

How to Cite
Al-Masoudi,  I. A.; Al-Souda, Y. A.; Al-Salihib, N. J.; Al-Masoudi, N. A.  Chem. Heterocycl. Compd. 2006, 42, 1377. [Khim. Geterotsikl. Soedin. 2006, 1605.]

For this article in the English edition see DOI 10.1007/s10593-006-0255-3


Keywords


1,2,4-triazoles; pharmacological properties; synthetic routes

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