6(7)-ACYLPERIMIDINES NITRATION AND METHODS OF <i>peri</i>-ANNELATION ON THIS BASE

Abstract

A method has been developed for the nitration of 6(7)-acylperimidines using sodium nitrite in formic acid. The reaction gives a mixture of 4(9)-, 9(4)-, and 7(6)-nitro-6(7)-acylperimidines from which the latter can be separated by extraction with chloroform. Reduction of the 6(7)-acyl-7(6)-nitroperimidines yields 1H-1,5,7-triazacyclopenta[cd]phenalenes. Subsequent Schmidt reaction and reduction give 1,3,6,8-tetraazapyrenes.

Authors: A. V. Aksenov, N. A. Aksenov, A. S. Lyakhovnenko, A. N. Smirnov, I. I. Levina, and I. V. Aksenova.

English Translation in Chemistry of Heterocyclic Compounds, 2013, 49 (7), pp 980-987

http://link.springer.com/article/10.1007/s10593-013-1335-9