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THREE-COMPONENT SYNTHESIS OF DIMETHYL 7-ARYL-8-(3-ARYLQUINOXALIN-2-YL)-2-(R-IMINO)-9-OXO-1,6-DIOXASPIRO[4.4]NONA-3,7-DIENE-3,4-DICARBOXYLATES

Н. Ю. Лисовенко, А. В. Дряхлов
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Abstract


We have developed a method for the synthesis of dimethyl 7-aryl-8-(3-arylquinoxalin-2‑yl)-2-(R-imino)-9‑oxo-1,6-dioxaspiro[4.4]nona-3,7-diene-3,4-dicarboxylates, based on a three-component reaction of 5-aryl-4-(quinoxalin-2-yl)furan-2,3-diones, 1-adamantylisocyanide or о-methylphenylisocyanide, and dimethyl acetylenedicarboxylate.

How to Cite
Lisovenko, N. Yu.; Dryahlov, A. V. Chem. Heterocycl. Compd. 2014, 50, 1. [Khim. Geterotsikl. Soedin. 2014, 5.]

For this article in the English edition see DOI 10.1007/s10593-014-1439-x

Keywords


5-aryl-4-(quinoxalin-2-yl)furan-2,3-diones; dimethyl acetylenedicarboxylate; dimethyl 7-aryl-8-(3-arylquinoxalin-2-yl)-2-(R-imino)-9-oxo-1,6-dioxaspiro[4.4]nona-3,7-diene-3,4-dicarboxylates; isocyanides; methyl 2-[5-aryl-4-(quinoxalin-2-yl)-3-oxo-2(3H)-furanylidene]acetate; γ-spiroiminolactones; multicomponent reaction

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