4-HYDROXY-2-QUINOLONES. 42. SYNTHESIS AND BIOLOGICAL ACTIVITY OF 1-R-2-OXO-3-(2H-1,2,4-BENZOTHIADIAZINE-1,1-DIOXID-3-YL)-4-HYDROXYQUINOLINES

Authors

  • И. В. Украинец National Pharmaceutical Academy of Ukraine
  • Е. А. Таран National Pharmaceutical Academy of Ukraine
  • О. В. Горохова National Pharmaceutical Academy of Ukraine
  • Нидаль Амин Джарадат National Pharmaceutical Academy of Ukraine
  • Л. Н. Воронина National Pharmaceutical Academy of Ukraine
  • И. В. Порохняк National Pharmaceutical Academy of Ukraine

DOI:

https://doi.org/10.1007/83

Keywords:

benzothiadiazine, diuretic, carbostyryl, 4-hydroxy-2-quinolone

Abstract

A preparative method for the synthesis of 1-R-2-oxo-3-(2H-1,2,4-benzothiadiazine-1,1-dioxid-3-yl)-4-hydroxyquinolines has been developed. The diuretic and antitubercular activity of the obtained compounds have been studied.

English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (3), pp 346-350

http://link.springer.com/article/10.1007/BF02256875

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Published

2012-12-05

Issue

No. 3 (2000)

Section

Original Papers