SYNTHESIS AND SPECTRAL FEATURES OF NEW 1-ALKYL-5-(INDOL-2(3)-YL)PYRROLIDIN-2-ONES

Authors

  • Н. Е. Мысова A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
  • А. Э. Ковров M. V. Lomonosov Moscow State University
  • А. В. Садовой M. V. Lomonosov Moscow State University
  • Л. А. Свиридова M. V. Lomonosov Moscow State University
  • Г. А. Голубева M. V. Lomonosov Moscow State University
  • Н. И. Ворожцов M. V. Lomonosov Moscow State University

DOI:

https://doi.org/10.1007/877

Keywords:

5-hydroxypyrrolidin-2-ones, indoles, amidoalkylation, mass spectrometry

Abstract

The mass spectrometric behavior of 1-alkyl-5-(1H-indol-2-yl)pyrrolidin-2-ones and 1-alkyl-5-(1H-indol-3‑yl)pyrrolidin-2-ones was studied and the fragmentation of these compounds was established. The product of N-methylindole reaction with 1-benzyl-5-hydroxypyrrolidin-2-one was shown to be 1‑benzyl-5-(1-methylindol-3-yl)pyrrolidin-2-one.

Authors: N. E. Mysova, A. E. Kovrov, A. V. Sadovoy, L. A. Sviridova, G. A. Golubeva, and N. I. Vorozhtsov

English Translation in Chemistry of Heterocyclic Compounds, 2012, 48 (11), pp 1634-1640

http://link.springer.com/article/10.1007/s10593-013-1185-5

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Published

2013-08-22

Issue

No. 11 (2012)

Section

Original Papers