THE SYNTHESIS AND CYTOTOXIC PROPERTIES OF SELENOPHENO[3,2-<i>c</i>]- AND SELENOPHENO[2,3-<i>c</i>]QUINOLONES

Authors

  • П. Арсенян Latvian Institute of Organic Synthesis
  • Е. Васильева Latvian Institute of Organic Synthesis
  • И. Шестакова Latvian Institute of Organic Synthesis
  • И. Домрачева Latvian Institute of Organic Synthesis
  • С. Беляков Latvian Institute of Organic Synthesis

DOI:

https://doi.org/10.1007/883

Keywords:

quinolone, selenium, selenophene, cytotoxicity, electrophilic addition, intramolecular cyclization, X-ray structural analysis

Abstract

We have developed a method for the synthesis of novel selenophene-containing polycyclic heterocycles, derivatives of selenopheno[3,2-c]- and selenopheno[2,3-c]quinolones. The cytotoxic activity of these compounds was studied in vitro. The molecular structure of 3-bromo-5-methyl-2-(piperidin-2‑ylmethyl)selenopheno[3,2-c]quinolin-4(5H)-one was confirmed by X-ray analysis.

How to Cite
Arsenyan, P.; Vasiljeva, J.; Shestakova, I.; Domracheva, I.; Belyakov, S. Chem. Heterocycl. Compd. 2014, 49, 1674. [Khim. Geterotsikl. Soedin. 2013, 1804.]

For this article in the English edition see DOI 10.1007/s10593-014-1419-1

Author Biography

П. Арсенян, Latvian Institute of Organic Synthesis

Павел Павлович Арсенян

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Published

2013-10-14

Issue

No. 11 (2013)

Section

Original Papers