PREPARATION OF BENZISOTHIAZOLONES FROM 2-BROMOBENZAMIDES AND SULFUR UNDER COPPER CATALYSIS CONDITIONS

Authors

  • В. Красикова Latvian Institute of Organic Synthesis
  • М. Каткевич Latvian Institute of Organic Synthesis

DOI:

https://doi.org/10.1007/889

Keywords:

benzisothiazolone, 2-bromobenzamide, sulfur, copper catalysis, S–N bond

Abstract

A convenient two-stage method has been developed for preparing benz[d]isothiazol-3(2H)-ones from 2-bromobenzamides and sulfur in a one-pot process under copper catalysis conditions. The method is suitable for the synthesis of N-aryl-, benzyl-, and alkyl-substituted benzisothiazolones. The yields of the benzisothiazolones depend on the nature of the starting amide and can reach 91%.

Authors: V. Krasikova and M. Katkevics

English Translation in Chemistry of Heterocyclic Compounds, 2012, 48 (11), pp 1684-1690

http://link.springer.com/article/10.1007/s10593-013-1193-5

Published

2013-08-27

Issue

Section

Original Papers