Open Access Open Access  Restricted Access Subscription Access

NANO SULFATED TITANIA AS A HETEROGENEOUS SOLID ACID CATALYST FOR THE SYNTHESIS OF PYRROLES BY CLAUSON–KASS CONDENSATION UNDER SOLVENT-FREE CONDITIONS

M. Hosseini-Sarvari, S. Najafvand-Derikvandi, A. Jarrahpour, R. Heiran
Cover Image

Abstract


A new and environmentally benign method for the preparation of N-substituted pyrroles from one-pot condensation reaction of 2,5-dimethoxytetrahydrofuran with amines and diamines in the presence of nano sulfated titania under solvent-free conditions is presented. This new protocol features simple operations, easy availability, stability, and eco-friendly catalyst, as well as high to excellent yields of products. In addition, we report for the first time an alternative method for the synthesis of pyrroles from aromatic amines containing β-lactam fragment using nano sulfated titania as catalyst.

How to Cite
Hosseini-Sarvari, M.; Najafvand-Derikvandi, S.; Jarrahpour, A.; Heiran, R. Chem. Heterocycl. Compd. 2014, 49, 1732. [Khim. Geterotsikl. Soedin. 2013, 1870.]

For this article in the English edition see DOI 10.1007/s10593-014-1425-3


Keywords


2,5-dimethoxytetrahydrofuran; nano sulfated titania; N-substituted pyrroles; Clauson–Kass condensation

Full Text: PDF (Russian) Supplementary File(s): None


 

 

Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv