Synthesis of pyrrolopyrimidines from 2,5-diaryl-3,3,4,4-tetracyanopyrrolidines

Authors

  • O. E. Насакин I. N. Ul'yanov Chubash State University, 428015 Cheboksary
  • А. Н. Лыщиков I. N. Ul'yanov Chubash State University, 428015 Cheboksary
  • П. М. Лукин I. N. Ul'yanov Chubash State University, 428015 Cheboksary
  • B. А. Tафеенко I. N. Ul'yanov Chubash State University, 428015 Cheboksary
  • А. Х. Булай I. N. Ul'yanov Chubash State University, 428015 Cheboksary

Abstract

Feasibility has been demonstrated for the synthesis of pyrrolo[1,2-a]pyrimidines by the reaction of 2,5-diaryl-3,3,4,4-tetracyanopyrrolidines I with β-dicarbonyl compounds, which was carried out by the rearrangement of I to give 2-(N-arylidenamino)-5-aryl-3,4-dicaynopyrroles II. A different pathway was found for the reaction of pyrroles II with β-diketones and ethyl acetoacetate. The existence of a latento-enaminonitrile fragment in these compounds permits their conversion to pyrrolo[2,3-d]pyrimidines.

How to Cite
Nasakin, O. E.; Lyshchikov, A.;N.; Lukin, P. M.; Tafeenko, V. A.; Bulai, A. Kh. Chem. Heterocycl. Compd. 1997, 33, 1450. [Khim. Geterotsikl. Soedin. 1997, 1676.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02291648

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Published

1997-12-25

Issue

No. 12 (1997)

Section

Original Papers