Synthesis of 4-alkyl-6-amino-3,5-dicyano-2(1H)-pyridinethiones

Authors

  • В. Д. Дяченко T. G. Shevchenko State Teaching Institute, Lugansk 348011
  • C. Г. Кривоколыско T. G. Shevchenko State Teaching Institute, Lugansk 348011
  • В. H. Нестеров A. N. Nesmeyanov Institute of Organoelemental Compounds, Moscow 117813
  • В. П. Литвинов N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 117913

Abstract

Condensation of aliphatic aldehydes with cyanothioacetamide has given 4-alkyl-6-amino-3,5-dicyano-2(1H)-pyridinethiones, which have also been synthesized by recyclization of 4-alkyl-2,6-diamino-4H-thiopyrans. Substituted 2-alkylthiopyridines and thieno[2,3-b]pyridines have been prepared from the pyridinethiones. 2,6-Diamino-4-isopropyl-3,5-dicyano-4H-thiopyran and 6-amino-4-isobutyl-2-methylthio-3,5-dicyanopyridine have been studied by X-ray crystallography.

How to Cite
Dyachenko, V. D.; Krivokolysko, S. G.; Nesterov, V. N.; Litvinov, V. P. Chem. Heterocycl. Compd. 1997, 33, 1430. [Khim. Geterotsikl. Soedin. 1997, 1655.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02291644

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Published

1997-12-25

Issue

No. 12 (1997)

Section

Original Papers