Synthesis of 6-methyl-5-phenylcarbamoyl-3,4-dihydropyridinespiro-4-cyclohexane-2(1H)-thione and its derivatives

Authors

  • B. Д. Дяченко T. G. Shevchenko Lugansk State Pedagogical Institute, Lugansk 348011
  • C. Г. Кривоколыско T. G. Shevchenko Lugansk State Pedagogical Institute, Lugansk 348011
  • В. П. Литвинов N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 117913

Abstract

3-Cyano-6-methyl-5-phenylcarbamoyl-3,4-dihydropyridinespiro-4-cyclohexane-2(1H)-thione was obtained by the condensation of acetoacetic acid anilide with cyclohexylidenecyanothioacetamide. Substituted 2-alkylthio-1,4-dihydropyridines and 3-amino-2-(4-chlorobenzoyl)-6-methyl-5-phenylcarbamoyl-4,7-dihydrothieno[2,3-b]pyridinespiro-4-cyclohexane were synthesized from it.

How to Cite
Dyachenko, V. D.; Krivokolysko, S. G.; Litvinov, V. P. Chem. Heterocycl. Compd. 1997, 33, 1325. [Khim. Geterotsikl. Soedin. 1997, 1533.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02320335

Published

1997-11-25

Issue

Section

Original Papers