Investigation of the oxidation-reduction transformations of derivatives of dipyrimido[4,5-<i>b</i>][4′,5′-<i>e</i>][1,4]thiazine

Authors

  • М. П. Немерюк Center of the Chemistry of Medicinals, All-Russian Scientific-Research Pharmaceutical Chemistry Institute, Moscow
  • H. Б. Григорьев Center of the Chemistry of Medicinals, All-Russian Scientific-Research Pharmaceutical Chemistry Institute, Moscow
  • H. И. Травень Center of the Chemistry of Medicinals, All-Russian Scientific-Research Pharmaceutical Chemistry Institute, Moscow
  • В. И. Левина Center of the Chemistry of Medicinals, All-Russian Scientific-Research Pharmaceutical Chemistry Institute, Moscow
  • E. B. Дехтярев Center of the Chemistry of Medicinals, All-Russian Scientific-Research Pharmaceutical Chemistry Institute, Moscow
  • Т. C. Сафонова Center of the Chemistry of Medicinals, All-Russian Scientific-Research Pharmaceutical Chemistry Institute, Moscow

Abstract

The oxidation-reduction characteristics of both the free radical and the reduced forms of dipyrimido[4,5-b][4′,5′-e][1,4]thiazine derivatives were studied by polarography. It was found that these compounds can participate in oxidation-reduction reactions, such as the oxidation of thiols and ascorbic acid (the radical form) and the reduction of oxygen (the reduced from). This makes it possible to regard them as a system capable of modelling certain oxidation-reduction processes that take place in the living organism.

How to Cite
Nemeryuk, M. P.; Grigor'ev, N. B.; Traven', N. I.; Levina, V. I.; Dekhtyarev, E. V.; Safonova, T. S. Chem. Heterocycl. Compd. 1997, 33, 1215. [Khim. Geterotsikl. Soedin. 1997, 1398.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02290873

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Published

1997-10-25

Issue

No. 10 (1997)

Section

Original Papers