Preparation and use of α-bromomono- and -bromobis-difluoromethoxyacetophenones in the synthesis of polymethyleneimidazoles with an angular nitrogen atom

Authors

  • А. М. Демченко T. G. Shevchenko Chernigov Pedagogical Institute, Chernigov 250038
  • К. Г. Назаренко Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 252660
  • Д. В. Фeдюк Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 252660
  • Ю. А. Фиaлков Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 252660
  • C. B. Шеляженко Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 252660
  • Л. M. Ягупольский Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 252660

Abstract

The synthesis of α-bromo-4-difluoromethoxy- and α-bromo-2,4-bis(difluoromethoxy)acetophenones has been carried out. Conditions have been studied for condensing the latter with cyclic tri- and tetramethylenamidinines and with pyridine-containing derivatives. A series of pyrrolo[1,2-a]imidazole and imidazo[2,1-a]pyridine derivatives containing difluoromethoxy groups has been synthesized.

How to Cite
Demchenko, A. M.; Nazarenko, K. G.; Fedyuk, D. V.; Fialkov, Yu. A.; Shelyazhenko, S. V.; Yagupol'skii, L. M. Chem. Heterocycl. Compd. 1997, 33, 1191. [Khim. Geterotsikl. Soedin. 1997, 1371.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02290868

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Published

1997-10-25

Issue

No. 10 (1997)

Section

Original Papers