Direction of alkylation of 5-aryl-1,3,4-oxadiazoline-2-thiones

Authors

  • А. А. Зияев Institute of the Chemistry of Vegetable Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent 700170
  • Г. Г. Галустьян Institute of the Chemistry of Vegetable Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent 700170

Abstract

The reaction of potassium salt of 5-(2,4-dichlorophenyl)-1,3,4-oxadiazoline-2-thione with dimethyl sulfate was carried out in water and HMPT. It was shown that the nature of the solvent affects the ratio of the formed products of S- and N-methylation. The alkylation of 5-aryl-1,3,4-oxadiazoline-2-thiones with isomeric butyl chlorides showed that the reaction takes place only with n-butyl chloride with the formation of the corresponding S-butyl-substituted derivative.

How to Cite
Ziyaev, A. A.; Galust'yan, G. G. Chem. Heterocycl. Compd. 1997, 33, 1109. [Khim. Geterotsikl. Soedin. 1997, 1268.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02253229

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Published

1997-09-25

Issue

No. 9 (1997)

Section

Original Papers