4-Hydroxy-2-quinolones. 35. Synthesis and study of antithyroid properties of 1H-2-oxo-3-(coumarin-3-yl)-4-hydroxyquinolines

Authors

  • И. B. Украинец Ukrainian Pharmaceutical Academy, Kharkhov 310002
  • C. Г. Таран Ukrainian Pharmaceutical Academy, Kharkhov 310002
  • O. Л. Кодолова Ukrainian Pharmaceutical Academy, Kharkhov 310002
  • O. B. Горохова Ukrainian Pharmaceutical Academy, Kharkhov 310002
  • B. H. Кравченко Ukrainian Pharmaceutical Academy, Kharkhov 310002

Abstract

The methyl ester of 1H-2-oxo-4-hydroxyquinoline-3-acetic acid is condensed in pyridine with salicylaldehydes to 1H-2-oxo-3-(coumarin-3-yl)-4-hydroxyquinolines. We present the results of a study of the effect of the synthesized compounds on thyroid function.

How to Cite
Ukrainets, I. V.; Taran, S .G.; Kodolova, O .L.; Gorokhova, O. V.; Kravchenko, V. N. Chem. Heterocycl. Compd. 1997, 33, 959. [Khim. Geterotsikl. Soedin. 1997, 1100.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02253169

Published

1997-08-25

Issue

Section

Original Papers