Synthesis of N-methylmorpholinium 6-methyl-4-(2-thienyl)-5-phenylcarbamoyl-3-cyano-1,4-dihydropyridine-2-thiolate and its reaction with various functionally substituted methyl halides

Abstract

Condensation of the anilide of acetoacetic acid, thiophene aldehyde, cyanothioacetamide and N-methyl-morpholine gave N-methylmorpholinium 6-methyl-4-(2-thienyl)-5-phenylcarbamoyl-3-cyano-1,4-dihydropyridine-2-thiolate which reacted with various halides ZCH₂Hal or H₂NCOCH(Ph)Cl to give substituted 2-ZCH₂-thio or 2-H₂NCOCH(Ph)-thio-1,4-dihydropyridines.

How to Cite
Dyachenko, V. D.; Krivokolysko, S. G.; Litvinov, V. P. Chem. Heterocycl. Compd. 1997, 33, 577. [Khim. Geterotsikl. Soedin. 1997, 666.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02291942