Stereochemistry and products of addition of <i>tert</i>-butylisonitrile at the carbonyl group of 3-hydroxypiperidin-4-ones

Abstract

The stereochemistry and products of addition of tert-butylisonitrile at the carbonyl group of 3-hydroxypiperidin-4-ones have been studied. A preparative method for synthesis of 3-hydroxyisonipecotic acid derivatives has been developed. The orientation of the carbon containing substituent on the quaternary carbon atom was shown using¹³C NMR vicinal ³J_C,H spin couplings.

How to Cite
Lakhvich, T. T.; Lakhvich, O. F.; Stanishevskii, L. S. Chem. Heterocycl. Compd. 1997, 33, 448. [Khim. Geterotsikl. Soedin. 1997, 523.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02321391