Reaction of 2-cyanoethane-1,1,2-tricarboxamide with α-alkylacroleins
Abstract
In the presence of catalytic amounts of triethylamine 2-cyanoethane-1,1,2-tricarboxamide forms Michael adducts with α-alkylacroleins. After two intramolecular cyclizations, the adducts are converted into 5-alkyl-6-amino-4-hydroxy-7-carbamoyl-2-oxo-1-cyano-3-azabicyclo[3.2.1]oct-6-enes.
How to Cite
Nasakin, O. E.; Pavlov, V. V.; Lyshchikov, A. N.; Lukin, P. M.; Khrustalev, V. N.; Antipin, N. Yu.; Urman, A. G. Chem. Heterocycl. Compd. 1996, 32, 1136. [Khim. Geterotsikl. Soedin. 1996, 1326.]
For this article in the English edition, see DOI https://doi.org/10.1007/BF01169222