Alkyl derivatives of 1-aryldihydro-4(1H,3H)-pyrimidinone-2-thiones and their structure

Abstract

The alkylation of 1-aryldihydro-4(1H,3H)-pyrimidinone-2-thiones goes through both at the thiol group and at the amide nitrogen atom of the heterocycle. Enlargement of the alkyl radical favors an increase in the portion of the N-alkyl derivative in the mixture. The influence of the folding of the heterocycle on its barrier to rotation around the Ph-N₁ bond was shown.

How to Cite
Mitskyavichyus, V. Y.; Bilinskaite, I. C. Chem. Heterocycl. Compd. 1996, 32, 1078. [Khim. Geterotsikl. Soedin. 1996, 1255.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01164716