Synthesis and three-dimensional structure of 3,5-dichloro-3,4,5,6-tetrahydropyridines

Authors

  • В. В. Кастрон Latvian Institute of Organic Synthesis, Riga LV-1006
  • А. Ф. Mишнeв Latvian Institute of Organic Synthesis, Riga LV-1006
  • И. А. Скрастиньш Latvian Institute of Organic Synthesis, Riga LV-1006
  • Г. Я. Дyбypc Latvian Institute of Organic Synthesis, Riga LV-1006

Abstract

The reaction of N-chlorosuccinimide with 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(2-difluoromethoxyphenyl)-1,4-dihydropyridine (phoridone) has been studied. Depending on the amount of chlorinating agent, 3,4,5,6-tetrahydropyridines with different degrees of chlorination were obtained. The three-dimensional structure of 3,5-dimethoxycarbonyl-4-(2-difluoromethoxyphenyl)-2-methyl-6-chloromethylene-3, 5-dichloro-3,4,5,6-tetrahydropyridine has been studied.

How to Cite
Kastron, V. V.; Mishnev, A. F.; Skrastin'sh, I. A.; Duburs, G. Ya. Chem. Heterocycl. Compd. 1995, 31, 974. [Khim. Geterotsikl. Soedin. 1995, 1118.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01170325

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Published

1995-08-25

Issue

No. 8 (1995)

Section

Original Papers