Pyridylethylation of optically active amines

Authors

  • Г. Оеме Institute of Organic Catalysis, Rostock City University, Rostock 18055.
  • И. Иовель Latvian Institute of Organic Synthesis, Riga LV-1006
  • К. Факлям Institute of Organic Catalysis, Rostock City University, Rostock 18055.
  • Э. Лукевиц Latvian Institute of Organic Synthesis, Riga LV-1006

Abstract

A study has been made of the addition of (R)- and (S)-1-phenylethylamines and (R)- and (S)-1cyclohexylethylamines to the C=C bond of 2- and 4-vinylpyridines in the presence of an acid catalyst. The corresponding monoadducts have been synthesized with high preparative yields. By reactions of these adducts with 2- and 4-vinylpyridines, bis-adducts have been obtained. All of the products had high optical purities (91‒99%, HPLC).

Как ссылаться
Oeme, G.; Iovel', I.; Faklyam, K.; Lukevits, E. Chem. Heterocycl. Compd. 1995, 31, 737. [Химия гетероцикл. соединений 1995, 843.]

Статья в английском издании журнала: DOI https://doi.org/10.1007/BF01169071

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Published

1995-06-25

Issue

No. 6 (1995)

Section

Original Papers