Synthesis and properties of furan derivatives. 4. Synthesis of 2,5-disubstituted 1,3,4-oxadiazoles containing furan fragments

Abstract

The condensation of hydrochloride sats of iminoesters of furan acids with hydrazides of carboxylic acids gives 2,5-disubstituted 1,3,4-oxadiazoles containing furan fragments. Such compounds are also formed in the condensation of hydrazides of 5-R-furan-2-carboxylic acids with hydrocloride salts of carboxylic acid iminoesters. The reaction of furan acids with hydrazine dihydrochloride in polyphosphoric acid gave symmetrically disubstituted 1,3,4-oxadiazoles containing furan fragments.

How to Cite
Karakhanov, R. A.; Kelarev, V. I.; Koshelev, V. N.; Morozova, G. V.; Dibi, A. Chem. Heterocycl. Compd. 1995, 31, 208. [Khim. Geterotsikl. Soedin. 1995, 238.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01169682