Synthesis of 2,5-disubstituted 1,3,4-oxadiazoles from trichloromethylarenes and acylhydrazines

Authors

  • И. C. Поддубный N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow
  • Л. И. Беленький N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow
  • M. M. Краюшкин N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow

Abstract

A preparative synthesis of 2,5-disubstituted 1,3,4-oxadiazoles by the reaction of trichloromethylarenes with hydrazides of carboxylic acids of the aliphatic, aromatic and heteroaromatic series in methanol or ethanol in the presence of pyridine was developed.

How to Cite
Poddubnyi, I. S.; Belen'skii, L. I.; Krayushkin, M. M. Chem. Heterocycl. Compd. 1994, 30, 602. [Khim. Geterotsikl. Soedin. 1994, 686.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01169843

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Published

1994-05-25

Issue

No. 5 (1994)

Section

Original Papers