Synthesis and psychotropic properties of bis(2-thenylidene)diamines and their silyl derivatives

Authors

  • Л. H. Хохлова Latvian Institute of Organic Synthesis, Riga LV-1006
  • C. Германе Latvian Institute of Organic Synthesis, Riga LV-1006
  • H. И. Ерчак Latvian Institute of Organic Synthesis, Riga LV-1006
  • Э. Лyкевиц Latvian Institute of Organic Synthesis, Riga LV-1006

Abstract

The condensation of diamines with the corresponding aldehydes gave bis(2-thenylidene)diamines and their silyl derivatives. The structure of the compounds has been confirmed by their PMR spectra. It has been shown that the introduction of the trimethylsilyl group increases the toxicity, prolongs the hexenal narcosis and the antihypoxy activity, has a positive effect on the memory processes, and has no influence on the coordination of movements, the muscle tone, and the body temperature. All compounds possess an antialcohol activity, whereby the silyl derivatives have the stronger one.

How to Cite
Khokhlova, L. N.; Germane, S.; Erchak, N. P.;  Lukevits, É. Chem. Heterocycl. Compd. 1994, 30, 279. [Khim. Geterotsikl. Soedin. 1994, 316.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01165691

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Published

1994-03-25

Issue

No. 3 (1994)

Section

Original Papers