2-Carbethoxymethyl-4H-3,1-benzoxazin-4-one, 6. Synthesis of some new 3-acylamino-4-oxaquinazolin-2-yl-acetic acid benzylamides as possible anticonvulsants

Authors

  • И. В. Украинец Ukrainian Pharmaceutical Academy, Kharkov 310002
  • O. B. Горохова Ukrainian Pharmaceutical Academy, Kharkov 310002
  • C. Г. Таран Ukrainian Pharmaceutical Academy, Kharkov 310002
  • П. А. Безуглый Ukrainian Pharmaceutical Academy, Kharkov 310002
  • А. В. Туров Ukrainian Pharmaceutical Academy, Kharkov 310002

Abstract

Aternative ways of synthesizing 3-amino-4-oxoquinazolin-2-yl-acetic and propionic acid benzylamides and their aryl derivatives were investigated. The conditions of conversion of the synthesized 2-substituted 3-aminoquinazolin-4-ones into the corresponding 2-hydroxypyrazolo-3-R-(5,1-b]quinazolin-9(1H)-ones were determined. The findings of a study of the anticonvulsant properties of the synthesized compounds are reported.

How to Cite
Ukrainets, I. V.; Gorokhova, O. V.; Taran, S. G.; Bezuglyi, P. A.;  Turov, A. V. Chem. Heterocycl. Compd. 1994, 30, 208. [Khim. Geterotsikl. Soedin. 1994, 229.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01165014

Published

1994-02-25

Issue

Section

Original Papers