Synthesis of (2-oxo-1-pyrrolidinyl)pyrimidines

Authors

  • Г. Г. Данагулян Yerevan Institute of National Economy, 375025, Yerevan
  • Н. Г. Бaласанян Yerevan Institute of National Economy, 375025, Yerevan
  • М. Г. Залинян Yerevan Institute of National Economy, 375025, Yerevan

Abstract

(2-Oxo-1-pyrrolidinyl)pyrimidines have been synthesized by thermal cyclization of certain N-(pyrimidinyl)-γ-aminobutyric acids. Reaction of 2-methyl-4-chloro-6-(2-oxo-1-pyrrolidinyl)pyrimidine with the sodium salts of acetone or acetophenone oximes gave the corresponding pyrimidinylketoximes. The iodomethylation of pyrrolidinylpyrimidines is reported.

How to Cite
Danagulyan, G. G.; Balasanyan, N. G.; Zalinyan, M. G. Chem. Heterocycl. Compd. 1993, 29, 1323. [Khim. Geterotsikl. Soedin. 1993, 1540.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF00532034

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Published

1993-11-25

Issue

No. 11 (1993)

Section

Original Papers