Synthesis and some conversions of 4-aryl-6-methyl-2-methoxy(phenyl)-5-nitro-1,4-dihydropyrimidines

Authors

  • Г. Я. Ременников Institute of Bioorganic Chemistry and Petroleum Chemistry, National Academy of Sciences of Ukraine, 253660, Kiev
  • И. B. Болдырев Institute of Bioorganic Chemistry and Petroleum Chemistry, National Academy of Sciences of Ukraine, 253660, Kiev
  • C. А. Кравченко Institute of Bioorganic Chemistry and Petroleum Chemistry, National Academy of Sciences of Ukraine, 253660, Kiev
  • В. B. Пироженко Institute of Bioorganic Chemistry and Petroleum Chemistry, National Academy of Sciences of Ukraine, 253660, Kiev

Abstract

The reaction of 1-arylidene-1-nitropropan-2-ones with O-methylisourea (or benzamidine) in the presence of aluminum oxide gave 4-aryl-6-methyl-2-methoxy(phenyl)-5-nitro-1,4-dihydropyrimidines. It was shown that the reactions of the compounds synthesized with electrophilic agents proceed at the exocyclic methyl group, as well as at the N(1), N(3), and C(5) atoms of the 1,4-dihydropyrimidine fragment of the molecule.

How to Cite
Remennikov, G. Ya.; Boldyrev, I. V.; Kravchenko, S. A.; Pirozhenko, V. V. Chem. Heterocycl. Compd. 1993, 29, 1200. [Khim. Geterotsikl. Soedin. 1993, 1398.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF00538068

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Published

1993-10-25

Issue

No. 10 (1993)

Section

Original Papers