SYNTHESIS OF 3-ARYL-5-DIETHOXYPHOSPHORYLETHYNE-4,5-DIHYDROISOXAZOLES

Authors

  • В. К. Брель Institute of Physiologically Active Compounds, Russian Academy of Sciences

DOI:

https://doi.org/10.1007/1167

Keywords:

arylnitrile oxides, 4, 5-dihydroisoxazoles, phosphonates, vinylacetylenes, 1, 3-dipolar cycloaddition

Abstract

A convenient preparative method has been developed for obtaining a vinylacetylene phosphonate. The reaction of arylnitrile oxides with 4-(diethylphosphoryl)-2-methylbut-1-en-3-yne proceeds as a regioselective 1,3-dipolar cycloaddition exclusively at the terminal double bond of vinylacetylene phosphonate.

Author: V. K. Brel'.

English Translation in Chemistry of Heterocyclic Compounds, 2012, 48 (6), pp 907-911

http://link.springer.com/article/10.1007/s10593-012-1075-2

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Published

2013-11-15

Issue

No. 6 (2012)

Section

Original Papers