SYNTHESIS AND PROPERTIES OF 4-(3-AMINOTHIENO[2,3-<i>b</i>]PYRIDIN-2-YL)COUMARINS

Authors

  • C. В. Горелов PJSC SIC "Borshchahivskiy Chemical Pharmaceutical Plant"
  • C. П. Бондаренко National University of Food Technology
  • М. С. Фрасинюк Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine,

DOI:

https://doi.org/10.1007/1177

Keywords:

4-chloromethylcoumarin, 5H-chromeno[3, 4-c]pyridin-5-one, 6H-chromeno[4, 3-d]thieno[3, 2-b, 5, 4-b']dipyridin-6-one, 1, 2-dihydropyridine, 4-(thieno[2, 3-b]pyridin-2-yl)coumarin, aminomethylation

Abstract

Substituted 4-[(3-cyanopyridin-2-yl)thiomethyl]coumarins have been synthesized by the alkylation of 2-mercapto-4,6-dimethylnicotinonitrile with 4-chloromethylcoumarins. Substituted 4-(3-amino-thieno[2,3-b]pyridin-2-yl)coumarins have been obtained by a subsequent intramolecular condensation of the methylene and cyano groups. 6H-Chromeno[4,3-d]thieno[3,2-b:5,4-b']dipyridin-6-ones were isolated as a result of the interaction of these compounds with aldehydes, and their aminomethyl derivatives were synthesized.

Authors: S. V. Gorelov, S. P. Bondarenko, and M. S. Frasinyuk.

English Translation in Chemistry of Heterocyclic Compounds, 2012, 48 (6), pp 955-962

http://link.springer.com/article/10.1007/s10593-012-1083-2

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Published

2013-11-19

Issue

No. 6 (2012)

Section

Original Papers