MULTICOMPONENT REACTIONS IN ALKALOID-BASED DRUG DISCOVERY

Authors

  • I. V. Magedov New Mexico Institute of Mining and Technology
  • A. Kornienko New Mexico Institute of Mining and Technology

DOI:

https://doi.org/10.1007/1288

Keywords:

alkaloid, cyanocycline A, luotonin, rigidin, tubulysin, drug discovery, multicomponent reactions

Abstract

Multicomponent reactions are emerging as a powerful tool in alkaloid-based drug discovery. This highlight describes several recent (all published in 2011) examples of the employment of multicomponent reactions for the synthesis of biologically active alkaloids and their medicinally relevant analogs.

Also published in Chemistry of Heterocyclic Compounds, 2012, 48 (1), pp 33-38

http://link.springer.com/article/10.1007/s10593-012-0965-7

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Published

2013-12-04

Issue

No. 1 (2012)

Section

Review Articles