A CONVENIENT SYNTHESIS AND STRUCTURAL ANALYSIS OF NOVEL 4,5,6,7-TETRAHYDRO-1<i>H</i>-INDAZOLES

Authors

  • K. Murugavel Department of Chemistry, Annamalai University
  • S. Amirthaganesan Division of Image and Information Engineering, Pukyong National University
  • R. T. Sabapathy Mohan Manonmaniyam Sundaranar University

DOI:

https://doi.org/10.1007/2835

Keywords:

cyclic β-keto esters, 1H-indazole, tetrahydroindazole, HMBC, NOESY spectra

Abstract

A new series of t-4-aryl-3,c-6-dihydroxy-6-methyl-4,5,6,7-tetrahydro-1H-indazole-r-5-carboxylic acid isopropyl ester have been synthesized by adopting a conventional method from cyclic β-keto esters. 1H, 13C NMR, and IR spectra for all the compounds were investigated. HMBC, HSQC, COSY, and NOESY spectra of the representative compounds were studied. Stereochemistry of a six-membered ring of the fused indazoles was such as of keto esters. From the HMBC correlations the indazole structure was confirmed as 1H-indazole.

How to Cite
Murugavel, K.; Amirthaganesan, S.; Sabapathy Mohan, R. T. Chem. Heterocycl. Compd. 2010, 46, 302. [Khim. Geterotsikl. Soedin. 2010, 386.]

For this article in the English edition see DOI 10.1007/s10593-010-0505-2

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Published

2015-12-03

Issue

No. 3 (2010)

Section

Original Papers