SYNTHESIS AND ANTIOXIDANT ACTIVITY OF SOME NEW <i>N</i>-ALKYLATED PYRAZOLE-CONTAINING BENZIMIDAZOLES

Authors

  • Mahesh Bellam Sri Venkateswara University, University Ave., Tirupati 517 502
  • Mohan Gundluru Sri Venkateswara University, University Ave., Tirupati 517 502
  • Santhisudha Sarva Sri Venkateswara University, University Ave., Tirupati 517 502
  • Sridevi Chadive Sri Padmavathi Women's Degree & P.G. College, University Ave., Tirupati 517 502
  • Vasudeva Reddy Netala Sri Venkateswara University, University Ave., Tirupati 517 502
  • Vijaya Tartte Sri Venkateswara University, University Ave., Tirupati 517 502
  • Suresh Reddy Cirandur Sri Venkateswara University, University Ave., Tirupati 517 502

DOI:

https://doi.org/10.1007/3260

Keywords:

benzimidazole, 2, 2-diphenyl-1-picrylhydrazyl, hydrogen peroxide, pyrazole, zinc chloride, antioxidant activity

Abstract

A series of new N-substituted pyrazole-containing benzimidazoles was synthesized starting from 1,2-diaminobenzene and pyrazole-
4-carbaldehyde in good yield. Antioxidant activity of all title compounds was assessed using 2,2-diphenyl-1-picrylhydrazyl and
hydrogen peroxide assays. Some of the synthesized compounds having benzyl substituent at the imidazole nitrogen exhibited good
activity in both assays.

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Published

2017-03-09

Issue

Vol. 53 No. 2 (2017)

Section

Original Papers