NITROGEN-CONTAINING ACETALS AND KETALS IN THE SYNTHESIS OF PYRROLIDINE DERIVATIVES
Keywords:γ-amidoacetals, γ-carbamatoacetals, ketals, pyrrolidine derivatives, γ-ureidoacetals, heterocyclization reaction
This review offers analysis and generalization of data regarding the synthesis of substituted pyrrolidines by using nitrogen-containing acetals and ketals as starting compounds published from year 2000 to 2016. Particular attention has been focused on the synthesis of pyrrolidines that are substituted at position 2. Biological activity data for several pyrrolidine derivatives are reported.
Authors: Andrey V. Smolobochkin, Almir S. Gazizov*, Alexander R. Burilov, Michael A. Pudovik