TETRACHLOROSILANE AND ZINC CHLORIDE AS A BINARY REAGENT FOR THE PREPARATION OF 2-AMINO-6-CHLOROPYRIDINE-3,5-DICARBONITRILE DERIVATIVES

Authors

  • Ahmed Mohamed Sheta Faculty of Science, Damietta University
  • Saad S. Elmorsy Faculty of Science, Mansoura University
  • Mohammad M. A. Mashaly Faculty of Science, Damietta University
  • Samy B. Said Faculty of Science, Damietta University

DOI:

https://doi.org/10.1007/3589

Keywords:

malononitrile, pyridine, tetrachlorosilane, zinc chloride, one-pot synthesis.

Abstract

A green one-pot method for efficient synthesis of 2-amino-6-chloropyridine-3,5-dicarbonitrile derivatives was developed, based on stirring of various aldehydes and malononitrile with tetrachlorosilane and zinc chloride under solvent-free conditions at room temperature for 3–10 h. The effects of zinc chloride and the reaction conditions were studied. Compounds were characterized by X-ray analysis and NMR spectroscopy.

Author Biographies

Ahmed Mohamed Sheta, Faculty of Science, Damietta University

Saad S. Elmorsy, Faculty of Science, Mansoura University

Mohammad M. A. Mashaly, Faculty of Science, Damietta University

Samy B. Said, Faculty of Science, Damietta University

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Published

2017-06-06

Issue

Vol. 53 No. 5 (2017)

Section

Original Papers