THREE-COMPONENT REACTION OF KETALS, ISONITRILES, AND TRIMETHYLSILYL AZIDE

Authors

  • Никита Е. Голанцов
  • Хунг М. Нгуен
  • Алексей В. Варламов
  • Александр В. Аксенов
  • Леонид Г. Воскресенский Peoples Friendship University of Russia

DOI:

https://doi.org/10.1007/3672

Keywords:

isonitrile, ketal, tetrazole, trimethylsilyl azide, Passerini reaction

Abstract

It was demonstrated that a ZnCl2-catalyzed three-component reaction of ketals, isonitriles, and trimethylsilyl azide led to 1,5-disubstituted tetrazoles in moderate to high yields.

 

Authors: Nikita E. Golantsov, Hung M. Nguyen, Aleksey V. Varlamov, Aleksander V. Aksenov, Leonid G. Voskressensky

 

Author Biography

Леонид Г. Воскресенский, Peoples Friendship University of Russia

Organic Chemistry Department, professor

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Published

2017-05-11

Issue

Vol. 53 No. 4 (2017): Multicomponent reactions in the synthesis of heterocycles

Section

Original Papers