FORMYLATION OF 3,4-DIHYDROPYRROLO[1,2-<i>a</i>]PYRAZINES
DOI:
https://doi.org/10.1007/369Keywords:
3, 4-dihydropyrrolo[1, 2-a]pyrazine, Vilsmeier formylationAbstract
Formylation of 3,4-dihydropyrrolo[1,2-a]pyrazines containing alkyl or aryl substituents at position 1 has been studied under the conditions of the Vilsmeier reaction. The direction of the reaction depends on the structure of 3,4-dihydropyrrolo[1,2-a]pyrazine starting materials. Formylation of 1-methyl-substituted 3,4-dihydropyrrolo[1,2-a]pyrazines occurs at the methyl group.
Authors: V. I. Terenin, N. A. Tselishcheva, E. V. Kabanova, A. P. Pleshkova, and N. V. Zyk.
English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (10), pp 1206-1212