CHEMOSELECTIVE IODINATION OF 6-SUBSTITUTED IMIDAZO[1,2-<i>a</i>]PYRIDINE

Authors

  • Chunshen Zhao Guizhou University
  • Fei Li Guizhou University
  • Shuo Yang Guizhou University
  • Li Liu Guizhou University
  • Zhuyan Huang
  • Huifang Chai Guiyang College of Traditional Chinese Medicine

DOI:

https://doi.org/10.1007/4093

Keywords:

imidazo[1, 2-a]pyridine, heteroaryl iodides, synthesis, X-ray diffraction.

Abstract

3- and 8-Iodoimidazo[1,2-a]pyridines were synthesized from imidazo[1,2-a]pyridine under different substitution conditions. The molecular electrostatic potential calculations were performed to investigate the chemoselectivity of the substitution reaction. The molecular structures of the target compounds were characterized by single crystal X-ray diffraction analysis.

Author Biographies

Chunshen Zhao, Guizhou University

Fei Li, Guizhou University

Shuo Yang, Guizhou University

Li Liu, Guizhou University

Zhuyan Huang

Huifang Chai, Guiyang College of Traditional Chinese Medicine

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Published

2018-06-27

Issue

Vol. 54 No. 5 (2018)

Section

Short Communications