SYNTHESIS OF FUNCTIONALIZED TRIAZOLO[1,5-<i>a</i>]PYRIMIDINE DERIVATIVES

Authors

  • Наталья В. Чечина V. N. Karazin Kharkiv National University
  • Надежда Н. Колос V. N. Karazin Kharkiv National University
  • Ирина В. Омельченко STC ''Institute of Single Crystals'', National Academy of Sciences of Ukraine
  • Владимир И. Мусатов STC ''Institute of Single Crystals'', National Academy of Sciences of Ukraine

DOI:

https://doi.org/10.1007/4329

Keywords:

acetoacetic ester, acetylacetone, arylglyoxal hydrates, 4, 7-dihydro[1, 2, 4]triazolo[1, 5-a]pyrimidines, 1H-1, 4-triazol-5-amine, Biginelli-like reaction, three-component condensation

Abstract

New triazolo[1,5-a]pyrimidines containing aroyl and acetyl or ester groups in the pyrimidine ring were synthesized in a process related to the Biginelli-like reaction, using hydrates of arylglyoxals, β-dicarbonyl compounds, and 1H-1,2,4-triazol-5-amine. Reaction was carried out in either sequential or one-pot procedure.

Author Biographies

Наталья В. Чечина, V. N. Karazin Kharkiv National University

аспирант

Надежда Н. Колос, V. N. Karazin Kharkiv National University

Надежда Николаевна Колос

кафедра органической химии, профессор

Ирина В. Омельченко, STC ''Institute of Single Crystals'', National Academy of Sciences of Ukraine

научный сотрудник

Владимир И. Мусатов, STC ''Institute of Single Crystals'', National Academy of Sciences of Ukraine

Владимир Иванович Мусатов

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Published

2018-02-17

Issue

Vol. 54 No. 1 (2018)

Section

Original Papers