AN EFFECTIVE METHOD FOR THE SYNTHESIS OF 1,5-DISUBSTITUTED 4-HALO-1<i>H</i>-1,2,3-TRIAZOLES FROM MAGNESIUM ACETYLIDES

Authors

  • Юлия В. Карсакова Moscow M. V. Lomonosov State University, 1, Build. 3, Leninskie Gory, Moscow 119991
  • Александр Ю. Смирнов Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997
  • Михаил С. Баранов Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997 Pirogov Russian National Research Medical University, 1 Ostrovityanova St., Moscow 117997

DOI:

https://doi.org/10.1007/4392

Keywords:

4-halo-1, 2, 3-triazoles, organomagnesium compounds, 1, 3-dipolar cycloaddition

Abstract

A simple one-pot two-stage method for the synthesis of disubstituted 4-chloro-, 4-bromo-, and 4-iodo-1,2,3-triazoles from terminal alkynes and organic azides is proposed.

Authors: Iuliia V. Karsakova, Alexander Yu. Smirnov*, Mikhail S. Baranov

Author Biographies

Юлия В. Карсакова, Moscow M. V. Lomonosov State University, 1, Build. 3, Leninskie Gory, Moscow 119991

Юлия Валерьевна Карсакова

Кафедра аналитической химии, аспирант

Александр Ю. Смирнов, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997

Александр Юрьевич Смирнов

Группа химии гетероциклических соединений

Михаил С. Баранов, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya St., Moscow 117997 Pirogov Russian National Research Medical University, 1 Ostrovityanova St., Moscow 117997

Михаил Сергеевич Баранов

Группа химии гетероциклических соединений

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Published

2018-08-27

Issue

Vol. 54 No. 7 (2018)

Section

Short Communications