SYNTHESIS OF 5-(5-AMINO-1<i>H</i>-PYRAZOL-1-YL)- 1,2,3-THIADIAZOLE-4-CARBOXYLIC ACID ETHYL ESTERS AND THEIR CYCLIZATION INTO PYRAZOLO[1,5-<i>a</i>][1,2,3]THIADIAZOLO[4,5-<i>e</i>]PYRIMIDIN-4(5<i>H</i>)-ONES

Authors

  • Ольга А. Высокова Ural Federal University named after the first President of Russia B. N. Yeltsin
  • Татьяна А. Калинина Ural Federal University named after the first President of Russia B. N. Yeltsin
  • Павел А. Слепухин I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences
  • Татьяна А. Поспелова Ural Federal University named after the first President of Russia B. N. Yeltsin
  • Константин Л. Обыденнов Ural Federal University named after the first President of Russia B. N. Yeltsin
  • Татьяна В. Глухарева Ural Federal University named after the first President of Russia B. N. Yeltsin; I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences

DOI:

https://doi.org/10.1007/4779

Keywords:

pyrazoles, pyrazolo[1, 5-a]pyrimidines, pyrimidin-4(3H)-ones, 1, 2, 3-thiadiazoles, fused heterocycles, tricyclic heterocycles, condensation, X-ray structural analysis

Abstract

A method for the synthesis of novel 1H-pyrazol-1-yl-1,2,3-thiadiazole derivatives has been proposed and their intramolecular cyclization to pyrazolo[1,5-a][1,2,3]thiadiazolo[4,5-e]pyrimidin-4(5H)-ones, previously unknown fused tricyclic heterocycles, has been studied.

Authors: Olga А. Vysokova, Tatiana A. Kalinina, Pavel А. Slepukhin,
Tatiana А. Pospelova, Konstantin L. Obydennov, Tatiana V. Glukhareva

 

Author Biography

Татьяна В. Глухарева, Ural Federal University named after the first President of Russia B. N. Yeltsin; I. Ya. Postovskii Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences

кафедра технологии органического синтеза, доцент

Downloads

Published

2018-12-12

Issue

Vol. 54 No. 11 (2018)

Section

Short Communications