SYNTHESIS OF FERROCENE-BASED POLYSUBSTITUTED PYRROLIDINES
DOI:
https://doi.org/10.1007/5045Keywords:
azomethine ylides, ferrocene, pyrrolidine, 1, 3-dipolar cycloaddition.Abstract
Ferrocene-based polysubstituted pyrrolidines can be synthesized efficiently via 1,3-dipolar cycloaddition of azomethine ylides generated from α-amino acid ester and ferrocenecarboxaldehyde with N-substituted maleimide at 125°C in MeCN. The structures of the products were confirmed by 1H, 13C NMR, and HRMS data.
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Published
2019-09-27
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Original Papers