SYNTHESIS AND ALKYLATION OF 3-CYANO-4-ISOBUTYL-5-OXO-1,4,5,6,7,8-HEXAHYDROQUINOLINE-2-THIOL
DOI:
https://doi.org/10.1007/535Abstract
By reaction of isovaleric aldehyde with cyanothioacetamide and cyclohexane-1,3-dione, 3-cyano-4-isobutyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-1-thiol has been obtained, and subsequently used in synthesis of the corresponding substituted 2-alkylthiohexahydroquinolines.
Authors: S. G. Krivokolysko, V. D. Dyachenko, and V. P. Litvinov.
English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (2), pp 206-207
http://link.springer.com/article/10.1007/BF02251711