SYNTHESIS OF α-SPIROCYCLIC PYRROLIDINES

Authors

  • Kostiantyn P. Melnykov Enamine Ltd.
  • Sergey V. Ryabukhin National Taras Shevchenko University of Kyiv

DOI:

https://doi.org/10.1007/5749

Keywords:

pyrrolidines, spirocycles, heterocyclization

Abstract

Different approaches and recent advances in methodologies for the synthesis of α-spirocyclic pyrrolidines are presented. The microreview covers the latest selected examples (2009–2019) on the synthesis of such compounds based on pyrrolidine ring construction. The advantages and features of the methods are discussed.

Author Biography

Sergey V. Ryabukhin, National Taras Shevchenko University of Kyiv

Professor of department of supramolecular chemistry. Institute of High Technologies.

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Published

2020-11-26

Issue

Vol. 56 No. 11 (2020)

Section

Heterocycles in Focus