2<i>H</i>-AZIRINES IN MEDICINAL CHEMISTRY

Authors

  • Павел А. Сахаров Institute of Chemistry, Saint Petersburg State University, 7/9 University Embankment, Saint Petersburg 199034, Russia
  • Михаил С. Новиков Institute of Chemistry, Saint Petersburg State University, 7/9 University Embankment, Saint Petersburg 199034, Russia
  • Николай В. Ростовский Institute of Chemistry, Saint Petersburg State University, 7/9 University Embankment, Saint Petersburg 199034, Russia

DOI:

https://doi.org/10.1007/6082

Keywords:

2Н-azirines, bioconjugation, biological activity, cycloaddition, natural compounds.

Abstract

The review presents an analysis of studies published in the period 1971–2020 devoted to examination of the biological activity of natural and synthetic 2H-azirine derivatives, their use for bioconjugation, as well as search for some new synthetic methods of structural modification of azirines with the aim of improving their biological activity.

 

Author Biography

Николай В. Ростовский, Institute of Chemistry, Saint Petersburg State University, 7/9 University Embankment, Saint Petersburg 199034, Russia

head of the department of organic chemistry

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Published

2021-05-26

Issue

Vol. 57 No. 5 (2021)

Section

Review Articles