SYNTHESIS OF NEW N-ALKYL(ARYL)-2,4-DIARYL-1H-PYRROLE-3-OLS <i>VIA</i> ALDOL–PAAL–KNORR REACTIONS

Authors

  • B. Eftekhari-Sis Department of Chemistry, Faculty of Science, University of Maragheh, Maragheh
  • A. Akbari Department of Chemistry, Faculty of Science, University of Maragheh, Maragheh
  • M. Amirabedi Faculty of Mechanics, Islamic Azad University of Ajabshir, Ajabshir

DOI:

https://doi.org/10.1007/6146

Keywords:

1, 4-diazabicyclo[2.2.2]oktane, phenylglyoxa, pyrrole derivatives, aldol reaction, PaalKnorr reaction

Abstract

New N-alkyl(aryl)-2,4-diaryl-1H-pyrrol-3-ol derivatives have been synthesized in moderate to good yields in a novel and efficient process by aldol reaction of 1-(4-methoxyphenyl)propan-2-ones with phenylglyoxal in the presence of DABCO in water, followed  by  Paal-Knorr reaction with amines in the presence of catalytic  amount  of p-TSA in toluene at reflux.

How to Cite

Eftekhari-Sis, ;Akbari, A.; Amirabedi, M. Chem. Heterocycl. Compd. 2011, 46, 1330. [Khim. Geterotsikl. Soedin. 2010, 1644.]

For this article in the English edition see DOI 10.1007/s10593-011-0669-4

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Published

2021-02-10

Issue

No. 11 (2010)

Section

Original Papers