NOVEL SYNTHESIS OF HIGHLY FUNCTIONALIZED PYRAZOLONE SYSTEMS <i>VIA</i> REARRANGEMENT OF 5-PHENYL-1-OXA- 5,6-DIAZASPIRO[2.4]HEPTANE-4,7-DIONES

Authors

  • S. A. M. Metwally Chemistry Department Assiut University, Assiut
  • T. A. Mohamed Chemistry Department Assiut University, Assiut
  • O. S. Moustafa Chemistry Department Assiut University, Assiut
  • Y. A. El-Ossaily Chemistry Department Assiut University, Assiut

DOI:

https://doi.org/10.1007/6148

Keywords:

3, 5-pyrazolidinediones, epoxidation, 15N NMR, ring transformation

Abstract

Epoxidation of 4-alkylidene(arylidene)-1-phenyl-3,5-pyrazolidine- diones using alkaline hydrogen peroxide gave the corresponding 5-phenyl-1-oxa-5,6-diazaspiro[2.4]heptane-4,7-dione derivatives.Their reaction with nucleophilic reagents was investigated. The resulting products depend on the type of the diazaspiro compound and/or the nucleophile used.

How to Cite

Metwally, S. A. M.; Mohamed, T. A.; Moustafa, O. S.; El-Ossaily, Y. A. Chem. Heterocycl. Compd. 2011, 46, 1344. [Khim. Geterotsikl. Soedin. 2010, 1659.]

For this article in the English edition see
DOI 10.1007/s10593-011-0671-x

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Published

2021-02-10

Issue

No. 11 (2010)

Section

Original Papers